THE DECISION TO TREAT FEVER : Do Antibiotics Reduce A Fever ?
Most fevers are associated with self-limited infection, such as common viral diseases. The use of antipyretics is not contraindicated in these infections: there is no significant clinical evidence that antipyretics delay the resolution of viral or bacterial infections, nor is there evidence that fever facilitaes recovery from infection or acts as an adjuvant to the immune system . In shorty, rotine treatment of fever and its symptoms with antipyretics does no harm and does not slow the resolution of common viral and bacterial infections.
know How Do Antibiotics Reduce A Fever?
TREATMENT : Regimens for the treatment of fever
Patients with temperatures greater than 41.0 degree Celsius requires prompt and vigorous treatment with antipyretics and poosibly external cooling measures. Temperatures above this range can result in damage to neuronal tissue. There is no evidence for improved outcome by routine use of antipyretic therapy, such as acetaminophen, in patients without exreme temperature elevation , but it is not harmful, and patients often feel better when their temperature declines. Achieving a normal or near -normal temperature is not necessary as a criterion for discharge , however . Patients with signs and symotoms of shock require prompt and vigorous treatment . Patients with evidence of respiratory failure from shock or pneumonia require ventilatory support. Soft tissue infection of the head and neck may compromise the airway because of mechanical obstruction. These may require acute intervention to provide a secure airway.
The objective in treating fever are first to reduce the elevator hypothalamic set point ans second to facilitate heat loss. Reducing fever with antipyretics also reduces systemic symptoms of headache, myalgias, and arthralgias.
PRINCIPLES OF ANTIBIOTIC THERAPY
The choice of an antibacterial compound for a particular patient and a specific infection involves more than just knowledge of the agent’s pharmacokinetic profile and in vitro activity. The basic tenets of chemotheraphy , to be elaborated below, include the following: When appropriate , material containing the infecting organism should be obtained before the start to treatment so that presumptive identification can be made by microscopic examination of stained specimes and the organism can be grown for definitive indentification and susceptibility testing. Awareness of local susceptibilty patternsis useful when the patients is treated empirically. If all other factors are equal, the least expensive antibacterial regimen should be chosen.